Rescue of ATXN3 neuronal toxicity in Caenorhabditis elegans by chemical modification of endoplasmic reticulum stress

Polyglutamine expansion diseases are a group of hereditary neurodegenerative disorders that develop when a CAG repeat in the causative genes is unstably expanded above a certain threshold. The expansion of trinucleotide CAG repeats causes hereditary adult-onset neurodegenerative disorders, such as H...

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Detalles Bibliográficos
Autores principales: Fardghassemi, Yasmin, Tauffenberger, Arnaud, Gosselin, Sarah, Parker, J. Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769603/
https://www.ncbi.nlm.nih.gov/pubmed/29061563
http://dx.doi.org/10.1242/dmm.029736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769603/
https://www.ncbi.nlm.nih.gov/pubmed/29061563
http://dx.doi.org/10.1242/dmm.029736

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