Cargando…

Rescue of ATXN3 neuronal toxicity in Caenorhabditis elegans by chemical modification of endoplasmic reticulum stress

Polyglutamine expansion diseases are a group of hereditary neurodegenerative disorders that develop when a CAG repeat in the causative genes is unstably expanded above a certain threshold. The expansion of trinucleotide CAG repeats causes hereditary adult-onset neurodegenerative disorders, such as H...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fardghassemi, Yasmin, Tauffenberger, Arnaud, Gosselin, Sarah, Parker, J. Alex
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769603/ https://www.ncbi.nlm.nih.gov/pubmed/29061563 http://dx.doi.org/10.1242/dmm.029736

Ejemplares similares

Heritable Transmission of Stress Resistance by High Dietary Glucose in Caenorhabditis elegans
por: Tauffenberger, Arnaud, et al.
Publicado: (2014)

Application of Caenorhabditis elegans for Research on Endoplasmic Reticulum Stress
por: Xu, Yuejia, et al.
Publicado: (2018)

TDP-1/TDP-43 Regulates Stress Signaling and Age-Dependent Proteotoxicity in Caenorhabditis elegans
por: Vaccaro, Alexandra, et al.
Publicado: (2012)

Modulating the endoplasmic reticulum stress response attenuates neurodegeneration in a Caenorhabditis elegans model of spinal muscular atrophy
por: Doyle, James J., et al.
Publicado: (2020)

Gene Expression Modifications by Temperature-Toxicants Interactions in Caenorhabditis elegans
por: Viñuela, Ana, et al.
Publicado: (2011)

Fragile lifespan expansion by dietary mitohormesis in C. elegans
por: Tauffenberger, Arnaud, et al.
Publicado: (2016)

Melatonin reduces the endoplasmic reticulum stress and polyubiquitinated protein accumulation induced by repeated anesthesia exposure in Caenorhabditis elegans
por: Shin, Hyun-Jung, et al.
Publicado: (2022)

Role of Unfolded Protein Response and Endoplasmic Reticulum-Associated Degradation by Repeated Exposure to Inhalation Anesthetics in Caenorhabditis elegans
por: Kim, Saeyeon, et al.
Publicado: (2021)

RNA‐Seq Reveals Acute Manganese Exposure Increases Endoplasmic Reticulum Related and Lipocalin mRNAs in Caenorhabditis elegans
por: Rudgalvyte, Martina, et al.
Publicado: (2015)

Compartmentalization of the endoplasmic reticulum in the early C. elegans embryos
por: Lee, Zuo Yen, et al.
Publicado: (2016)

Classification and prediction of toxicity of chemicals using an automated phenotypic profiling of Caenorhabditis elegans
por: Gao, Shan, et al.
Publicado: (2018)

Combined overexpression of ATXN1L and mutant ATXN1 knockdown by AAV rescue motor phenotypes and gene signatures in SCA1 mice
por: Carrell, Ellie M., et al.
Publicado: (2022)

F-actin asymmetry and the endoplasmic reticulum–associated TCC-1 protein contribute to stereotypic spindle movements in the Caenorhabditis elegans embryo
por: Berends, Christian W. H., et al.
Publicado: (2013)

Chemically defined medium and Caenorhabditis elegans
por: Szewczyk, Nathaniel J, et al.
Publicado: (2003)

Dapagliflozin rescues endoplasmic reticulum stress-mediated cell death
por: Shibusawa, Ryo, et al.
Publicado: (2019)

Study on the Combined Toxicities and Quantitative Characterization of Toxicity Sensitivities of Three Flavor Chemicals and Their Mixtures to Caenorhabditis elegans
por: Lu, Sheng, et al.
Publicado: (2021)

Curcumin rescues Caenorhabditis elegans from a Burkholderia pseudomallei infection
por: Eng, Su-Anne, et al.
Publicado: (2015)

Analysis of (CAG)(n) expansion in ATXN1, ATXN2 and ATXN3 in Chinese patients with multiple system atrophy
por: Zhou, X., et al.
Publicado: (2018)

Mutant TDP-43 and FUS Cause Age-Dependent Paralysis and Neurodegeneration in C. elegans
por: Vaccaro, Alexandra, et al.
Publicado: (2012)

CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stress
por: De Lorenzo, Francesca, et al.
Publicado: (2023)

Worming forward: amyotrophic lateral sclerosis toxicity mechanisms and genetic interactions in Caenorhabditis elegans
por: Therrien, Martine, et al.
Publicado: (2014)

Molecular characterization of ethyl carbamate toxicity in Caenorhabditis elegans
por: Comfort, Jordan J., et al.
Publicado: (2022)

Role of endoplasmic reticulum stress in drug‐induced toxicity
por: Foufelle, Fabienne, et al.
Publicado: (2016)

Endoplasmic reticulum stress in amelogenesis imperfecta and phenotypic rescue using 4-phenylbutyrate
por: Brookes, Steven J., et al.
Publicado: (2014)

Endoplasmic reticulum stress in human chronic wound healing: Rescue by 4‐phenylbutyrate
por: Bachar‐Wikstrom, Etty, et al.
Publicado: (2020)

Chemical reprogramming of Caenorhabditis elegans germ cell fate
por: Morgan, Clinton T., et al.
Publicado: (2009)

Ketamine induces apical extracellular matrix modifications in Caenorhabditis elegans
por: Yücel, Duygu
Publicado: (2022)

Chemical Modulation of Mitochondria–Endoplasmic Reticulum Contact Sites
por: Magalhães Rebelo, Ana Paula, et al.
Publicado: (2020)

Endocrine-Disrupting Chemicals and Their Adverse Effects on the Endoplasmic Reticulum
por: Kim, Kangmin, et al.
Publicado: (2022)

Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies
por: Park, Sangeun, et al.
Publicado: (2019)

Reduction of mutant ATXN1 rescues premature death in a conditional SCA1 mouse model
por: Orengo, James P., et al.
Publicado: (2022)

Histidine Protects Against Zinc and Nickel Toxicity in Caenorhabditis elegans
por: Murphy, John T., et al.
Publicado: (2011)

Sublethal Toxicity Endpoints of Heavy Metals to the Nematode Caenorhabditis elegans
por: Jiang, Ying, et al.
Publicado: (2016)

Multi-Toxic Endpoints of the Foodborne Mycotoxins in Nematode Caenorhabditis elegans
por: Yang, Zhendong, et al.
Publicado: (2015)

A method for measuring sulfide toxicity in the nematode Caenorhabditis elegans
por: Livshits, Leonid, et al.
Publicado: (2017)

Reproductive Toxicity of Furfural Acetone in Meloidogyne incognita and Caenorhabditis elegans
por: Cheng, Wanli, et al.
Publicado: (2022)

Control of Neuronal Network in Caenorhabditis elegans
por: Badhwar, Rahul, et al.
Publicado: (2015)

Caenorhabditis Elegans
Publicado: (2000)

Phenylbutyric Acid Rescues Endoplasmic Reticulum Stress-Induced Suppression of APP Proteolysis and Prevents Apoptosis in Neuronal Cells
por: Wiley, Jesse C., et al.
Publicado: (2010)

Endoplasmic reticulum-translocation is essential for APOL1 cellular toxicity
por: Kruzel-Davila, Etty, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_he7064a7aipvmrjqfaaed24bpi