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Evaluation of human dermal fibroblasts directly reprogrammed to adipocyte-like cells as a metabolic disease model

Adipose tissue is the primary tissue affected in most single gene forms of severe insulin resistance, and growing evidence has implicated it as a site at which many risk alleles for insulin resistance identified in population-wide studies might exert their effect. There is thus increasing need for h...

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Detalles Bibliográficos
Autores principales: Chen, Jian-Hua, Goh, Kim Jee, Rocha, Nuno, Groeneveld, Matthijs P., Minic, Marina, Barrett, Timothy G., Savage, David, Semple, Robert K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769609/
https://www.ncbi.nlm.nih.gov/pubmed/28982679
http://dx.doi.org/10.1242/dmm.030981