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Cohesin mediates Esco2-dependent transcriptional regulation in a zebrafish regenerating fin model of Roberts Syndrome

Robert syndrome (RBS) and Cornelia de Lange syndrome (CdLS) are human developmental disorders characterized by craniofacial deformities, limb malformation and mental retardation. These birth defects are collectively termed cohesinopathies as both arise from mutations in cohesion genes. CdLS arises d...

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Detalles Bibliográficos
Autores principales: Banerji, Rajeswari, Skibbens, Robert V., Iovine, M. Kathryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769645/
https://www.ncbi.nlm.nih.gov/pubmed/29084713
http://dx.doi.org/10.1242/bio.026013