The global origins of resistance-associated variants in the non-structural proteins 5A and 5B of the hepatitis C virus

New, costly, fast acting, therapies targeting the non-structural proteins 5A and 5B (NS5A and NS5B) regions of the hepatitis C virus (HCV) genome are curative in the majority of cases. Variants with certain mutations in the NS5A and NS5B regions of HCV have been shown to reduce susceptibility to dir...

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Detalles Bibliográficos
Autores principales: Jones, Bradley R, Howe, Anita Y M, Harrigan, P Richard, Joy, Jeffrey B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769712/
https://www.ncbi.nlm.nih.gov/pubmed/29362671
http://dx.doi.org/10.1093/ve/vex041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769712/
https://www.ncbi.nlm.nih.gov/pubmed/29362671
http://dx.doi.org/10.1093/ve/vex041

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