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The global origins of resistance-associated variants in the non-structural proteins 5A and 5B of the hepatitis C virus
New, costly, fast acting, therapies targeting the non-structural proteins 5A and 5B (NS5A and NS5B) regions of the hepatitis C virus (HCV) genome are curative in the majority of cases. Variants with certain mutations in the NS5A and NS5B regions of HCV have been shown to reduce susceptibility to dir...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769712/ https://www.ncbi.nlm.nih.gov/pubmed/29362671 http://dx.doi.org/10.1093/ve/vex041 |