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The RNA exosome and RNA exosome-linked disease

The RNA exosome is an evolutionarily conserved, ribonuclease complex that is critical for both processing and degradation of a variety of RNAs. Cofactors that associate with the RNA exosome likely dictate substrate specificity for this complex. Recently, mutations in genes encoding both structural s...

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Detalles Bibliográficos
Autores principales: Morton, Derrick J., Kuiper, Emily G., Jones, Stephanie K., Leung, Sara W., Corbett, Anita H., Fasken, Milo B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769741/
https://www.ncbi.nlm.nih.gov/pubmed/29093021
http://dx.doi.org/10.1261/rna.064626.117