Accurate detection of chemical modifications in RNA by mutational profiling (MaP) with ShapeMapper 2

Mutational profiling (MaP) enables detection of sites of chemical modification in RNA as sequence changes during reverse transcription (RT), subsequently read out by massively parallel sequencing. We introduce ShapeMapper 2, which integrates careful handling of all classes of adduct-induced sequence...

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Detalles Bibliográficos
Autores principales: Busan, Steven, Weeks, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769742/
https://www.ncbi.nlm.nih.gov/pubmed/29114018
http://dx.doi.org/10.1261/rna.061945.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769742/
https://www.ncbi.nlm.nih.gov/pubmed/29114018
http://dx.doi.org/10.1261/rna.061945.117

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