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Accurate detection of chemical modifications in RNA by mutational profiling (MaP) with ShapeMapper 2
Mutational profiling (MaP) enables detection of sites of chemical modification in RNA as sequence changes during reverse transcription (RT), subsequently read out by massively parallel sequencing. We introduce ShapeMapper 2, which integrates careful handling of all classes of adduct-induced sequence...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769742/ https://www.ncbi.nlm.nih.gov/pubmed/29114018 http://dx.doi.org/10.1261/rna.061945.117 |