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A microRNA feedback loop regulates global microRNA abundance during aging
Expression levels of many microRNAs (miRNAs) change during aging, notably declining globally in a number of organisms and tissues across taxa. However, little is known about the mechanisms or the biological relevance for this change. We investigated the network of genes that controls miRNA transcrip...
Autores principales: | Inukai, Sachi, Pincus, Zachary, de Lencastre, Alexandre, Slack, Frank J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769744/ https://www.ncbi.nlm.nih.gov/pubmed/29114017 http://dx.doi.org/10.1261/rna.062190.117 |
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