HIV-1 NC-induced stress granule assembly and translation arrest are inhibited by the dsRNA binding protein Staufen1

The nucleocapsid (NC) is an N-terminal protein derived from the HIV-1 Gag precursor polyprotein, pr55(Gag). NC possesses key functions at several pivotal stages of viral replication. For example, an interaction between NC and the host double-stranded RNA-binding protein Staufen1 was shown to regulat...

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Detalles Bibliográficos
Autores principales: Rao, Shringar, Cinti, Alessandro, Temzi, Abdelkrim, Amorim, Raquel, You, Ji Chang, Mouland, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769749/
https://www.ncbi.nlm.nih.gov/pubmed/29127210
http://dx.doi.org/10.1261/rna.064618.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769749/
https://www.ncbi.nlm.nih.gov/pubmed/29127210
http://dx.doi.org/10.1261/rna.064618.117

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