C3aR and C5aR1 act as key regulators of human and mouse β-cell function

AIMS: Complement components 3 and 5 (C3 and C5) play essential roles in the complement system, generating C3a and C5a peptides that are best known as chemotactic and inflammatory factors. In this study we characterised islet expression of C3 and C5 complement components, and the impact of C3aR and C...

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Detalles Bibliográficos
Autores principales: Atanes, Patricio, Ruz-Maldonado, Inmaculada, Pingitore, Attilio, Hawkes, Ross, Liu, Bo, Zhao, Min, Huang, Guo Cai, Persaud, Shanta J., Amisten, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769825/
https://www.ncbi.nlm.nih.gov/pubmed/28921001
http://dx.doi.org/10.1007/s00018-017-2655-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769825/
https://www.ncbi.nlm.nih.gov/pubmed/28921001
http://dx.doi.org/10.1007/s00018-017-2655-1

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