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Identification of New Potential APE1 Inhibitors by Pharmacophore Modeling and Molecular Docking
Apurinic/apyrimidinic endonuclease 1 (APE1) is an enzyme responsible for the initial step in the base excision repair pathway and is known to be a potential drug target for treating cancers, because its expression is associated with resistance to DNA-damaging anticancer agents. Although several inhi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Society of Gastrointestinal Intervention
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769857/ https://www.ncbi.nlm.nih.gov/pubmed/29307141 http://dx.doi.org/10.5808/GI.2017.15.4.147 |