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Identification of New Potential APE1 Inhibitors by Pharmacophore Modeling and Molecular Docking

Apurinic/apyrimidinic endonuclease 1 (APE1) is an enzyme responsible for the initial step in the base excision repair pathway and is known to be a potential drug target for treating cancers, because its expression is associated with resistance to DNA-damaging anticancer agents. Although several inhi...

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Detalles Bibliográficos
Autores principales:	Lee, In Won, Yoon, Jonghwan, Lee, Gunhee, Lee, Minho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society of Gastrointestinal Intervention 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769857/ https://www.ncbi.nlm.nih.gov/pubmed/29307141 http://dx.doi.org/10.5808/GI.2017.15.4.147

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