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In colonic ρ(0) (rho0) cells reduced mitochondrial function mediates transcriptomic alterations associated with cancer

BACKGROUND: Mitochondrial reprogramming has emerged as a hallmark of cancer pathobiology. Although it is believed this reprogramming is essential for cancer cells to thrive, how it supports cancer pathobiology is unclear. We previously generated colonic ρ0 (rho0) cells with reduced mitochondrial ene...

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Detalles Bibliográficos
Autores principales: Penrose, Harrison M., Heller, Sandra, Cable, Chloe, Nakhoul, Hani, Ungerleider, Nate, Baddoo, Melody, Pursell, Zachary F., Flemington, Erik K., Crawford, Susan E., Savkovic, Suzana D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769983/
https://www.ncbi.nlm.nih.gov/pubmed/29344557
http://dx.doi.org/10.18632/oncoscience.386