A pharmacological screen for compounds that rescue the developmental lethality of a Drosophila ATM mutant

Ataxia-telangiectasia (A-T) is a neurodegenerative disease caused by mutation of the A-T mutated (ATM) gene. ATM encodes a protein kinase that is activated by DNA damage and phosphorylates many proteins, including those involved in DNA repair, cell cycle control, and apoptosis. Characteristic biolog...

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Detalles Bibliográficos
Autores principales: Rimkus, Stacey A., Wassarman, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770031/
https://www.ncbi.nlm.nih.gov/pubmed/29338042
http://dx.doi.org/10.1371/journal.pone.0190821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770031/
https://www.ncbi.nlm.nih.gov/pubmed/29338042
http://dx.doi.org/10.1371/journal.pone.0190821

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