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Context-dependent autoprocessing of human immunodeficiency virus type 1 protease precursors

HIV-1 protease autoprocessing is responsible for liberation of free mature protease (PR) from the Gag-Pol polyprotein precursor. A cell-based model system was previously developed to examine the autoprocessing mechanism of fusion precursors carrying the p6*-PR miniprecursor sandwiched between variou...

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Detalles Bibliográficos
Autores principales: Tien, ChihFeng, Huang, Liangqun, Watanabe, Susan M., Speidel, Jordan T., Carter, Carol A., Chen, Chaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770051/
https://www.ncbi.nlm.nih.gov/pubmed/29338056
http://dx.doi.org/10.1371/journal.pone.0191372