Cargando…
Context-dependent autoprocessing of human immunodeficiency virus type 1 protease precursors
HIV-1 protease autoprocessing is responsible for liberation of free mature protease (PR) from the Gag-Pol polyprotein precursor. A cell-based model system was previously developed to examine the autoprocessing mechanism of fusion precursors carrying the p6*-PR miniprecursor sandwiched between variou...
Autores principales: | Tien, ChihFeng, Huang, Liangqun, Watanabe, Susan M., Speidel, Jordan T., Carter, Carol A., Chen, Chaoping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770051/ https://www.ncbi.nlm.nih.gov/pubmed/29338056 http://dx.doi.org/10.1371/journal.pone.0191372 |
Ejemplares similares
-
Targeting HIV-1 Protease Autoprocessing for High-throughput Drug Discovery and Drug Resistance Assessment
por: Huang, Liangqun, et al.
Publicado: (2019) -
Autoprocessing of human immunodeficiency virus type 1 protease miniprecursor fusions in mammalian cells
por: Huang, Liangqun, et al.
Publicado: (2010) -
Cysteine 95 and other residues influence the regulatory effects of Histidine 69 mutations on Human Immunodeficiency Virus Type 1 protease autoprocessing
por: Huang, Liangqun, et al.
Publicado: (2010) -
Flexible catalytic site conformations implicated in modulation of HIV-1 protease autoprocessing reactions
por: Huang, Liangqun, et al.
Publicado: (2011) -
A Functional Interplay between Human Immunodeficiency Virus Type 1 Protease Residues 77 and 93 Involved in Differential Regulation of Precursor Autoprocessing and Mature Protease Activity
por: Counts, Christopher J., et al.
Publicado: (2015)