Ultrasound-mediated delivery and distribution of polymeric nanoparticles in the normal brain parenchyma of a metastatic brain tumour model

The treatment of brain diseases is hindered by the blood-brain barrier (BBB) preventing most drugs from entering the brain. Focused ultrasound (FUS) with microbubbles can open the BBB safely and reversibly. Systemic drug injection might induce toxicity, but encapsulation into nanoparticles reduces a...

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Detalles Bibliográficos
Autores principales: Baghirov, Habib, Snipstad, Sofie, Sulheim, Einar, Berg, Sigrid, Hansen, Rune, Thorsen, Frits, Mørch, Yrr, Davies, Catharina de Lange, Åslund, Andreas K. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770053/
https://www.ncbi.nlm.nih.gov/pubmed/29338016
http://dx.doi.org/10.1371/journal.pone.0191102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770053/
https://www.ncbi.nlm.nih.gov/pubmed/29338016
http://dx.doi.org/10.1371/journal.pone.0191102

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