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Pre-existing malignancy results in increased prevalence of distinct populations of CD4(+) T cells during sepsis

The presence of pre-existing malignancy in murine hosts results in increased immune dysregulation and risk of mortality following a septic insult. Based on the known systemic immunologic changes that occur in cancer hosts, we hypothesized that the presence of pre-existing malignancy would result in...

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Detalles Bibliográficos
Autores principales: Xie, Jianfeng, Robertson, Jennifer M., Chen, Ching-wen, Zhang, Wenxiao, Coopersmith, Craig M., Ford, Mandy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770055/
https://www.ncbi.nlm.nih.gov/pubmed/29338031
http://dx.doi.org/10.1371/journal.pone.0191065