Cargando…
Pre-existing malignancy results in increased prevalence of distinct populations of CD4(+) T cells during sepsis
The presence of pre-existing malignancy in murine hosts results in increased immune dysregulation and risk of mortality following a septic insult. Based on the known systemic immunologic changes that occur in cancer hosts, we hypothesized that the presence of pre-existing malignancy would result in...
Autores principales: | Xie, Jianfeng, Robertson, Jennifer M., Chen, Ching-wen, Zhang, Wenxiao, Coopersmith, Craig M., Ford, Mandy L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770055/ https://www.ncbi.nlm.nih.gov/pubmed/29338031 http://dx.doi.org/10.1371/journal.pone.0191065 |
Ejemplares similares
-
TIGIT modulates sepsis-induced immune dysregulation in mice with preexisting malignancy
por: Zhang, Wenxiao, et al.
Publicado: (2021) -
Phenotypic T Cell Exhaustion in a Murine Model of Bacterial Infection in the Setting of Pre-Existing Malignancy
por: Mittal, Rohit, et al.
Publicado: (2014) -
Increased mortality in CD43-deficient mice during sepsis
por: Fay, Katherine T., et al.
Publicado: (2018) -
CXCR4 blockade decreases CD4(+) T cell exhaustion and improves survival in a murine model of polymicrobial sepsis
por: Ramonell, Kimberly M., et al.
Publicado: (2017) -
The IL-27 receptor regulates TIGIT on memory CD4(+) T cells during sepsis
por: Morrow, Kristen N., et al.
Publicado: (2021)