Cargando…

Exogenous miR-29B Delivery Through a Hyaluronan-Based Injectable System Yields Functional Maintenance of the Infarcted Myocardium

Myocardial infarction (MI) results in debilitating remodeling of the myocardial extracellular matrix (ECM). In this proof-of-principle study it was sought to modulate this aggressive remodeling by injecting a hyaluronic acid-based reservoir delivering exogenous microRNA-29B (miR-29B). This proof-of-...

Descripción completa

Detalles Bibliográficos
Autores principales: Monaghan, Michael G., Holeiter, Monika, Brauchle, Eva, Layland, Shannon L., Lu, Yan, Deb, Arjun, Pandit, Abhay, Nsair, Ali, Schenke-Layland, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770094/
https://www.ncbi.nlm.nih.gov/pubmed/28463641
http://dx.doi.org/10.1089/ten.tea.2016.0527