Cargando…

Exogenous miR-29B Delivery Through a Hyaluronan-Based Injectable System Yields Functional Maintenance of the Infarcted Myocardium

Myocardial infarction (MI) results in debilitating remodeling of the myocardial extracellular matrix (ECM). In this proof-of-principle study it was sought to modulate this aggressive remodeling by injecting a hyaluronic acid-based reservoir delivering exogenous microRNA-29B (miR-29B). This proof-of-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Monaghan, Michael G., Holeiter, Monika, Brauchle, Eva, Layland, Shannon L., Lu, Yan, Deb, Arjun, Pandit, Abhay, Nsair, Ali, Schenke-Layland, Katja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770094/ https://www.ncbi.nlm.nih.gov/pubmed/28463641 http://dx.doi.org/10.1089/ten.tea.2016.0527

Ejemplares similares

A Collagen-based Scaffold Delivering Exogenous MicroRNA-29B to Modulate Extracellular Matrix Remodeling
por: Monaghan, Michael, et al.
Publicado: (2014)

Steps toward Maturation of Embryonic Stem Cell-Derived Cardiomyocytes by Defined Physical Signals
por: Shen, Nian, et al.
Publicado: (2017)

Non-invasive Chamber-Specific Identification of Cardiomyocytes in Differentiating Pluripotent Stem Cells
por: Brauchle, Eva, et al.
Publicado: (2016)

Raman spectroscopy in biomedicine – non-invasive in vitro analysis of cells and extracellular matrix components in tissues
por: Brauchle, Eva, et al.
Publicado: (2013)

Surface functionalization of electrospun scaffolds using recombinant human decorin attracts circulating endothelial progenitor cells
por: Hinderer, Svenja, et al.
Publicado: (2018)

Generation and Assessment of Functional Biomaterial Scaffolds for Applications in Cardiovascular Tissue Engineering and Regenerative Medicine
por: Hinderer, Svenja, et al.
Publicado: (2015)

Exploring the relationship between epigenetic DNA methylation and cardiac fibrosis through Raman microspectroscopy
por: Becker, Lucas, et al.
Publicado: (2023)

Cell death stages in single apoptotic and necrotic cells monitored by Raman microspectroscopy
por: Brauchle, Eva, et al.
Publicado: (2014)

Endocardial-to-mesenchymal transformation and mesenchymal cell colonization at the onset of human cardiac valve development
por: Monaghan, Michael G., et al.
Publicado: (2016)

Controlled Heterotypic Pseudo-Islet Assembly of Human β-Cells and Human Umbilical Vein Endothelial Cells Using Magnetic Levitation
por: Urbanczyk, Max, et al.
Publicado: (2020)

Raman Spectroscopic Analyses of Jaw Periosteal Cell Mineralization
por: Brauchle, Eva, et al.
Publicado: (2017)

Trans-Mucosal Efficacy of Non-Thermal Plasma Treatment on Cervical Cancer Tissue and Human Cervix Uteri by a Next Generation Electrosurgical Argon Plasma Device
por: Wenzel, Thomas, et al.
Publicado: (2020)

Enabling Multiphoton and Second Harmonic Generation Imaging in Paraffin-Embedded and Histologically Stained Sections
por: Monaghan, Michael G., et al.
Publicado: (2016)

Non-invasive detection of DNA methylation states in carcinoma and pluripotent stem cells using Raman microspectroscopy and imaging
por: Daum, Ruben, et al.
Publicado: (2019)

Nidogen‐1 Mitigates Ischemia and Promotes Tissue Survival and Regeneration
por: Zbinden, Aline, et al.
Publicado: (2020)

Prospects for regenerative medicine approaches in women's health
por: Schenke‐Layland, Katja, et al.
Publicado: (2015)

Raman Imaging and Fluorescence Lifetime Imaging Microscopy for Diagnosis of Cancer State and Metabolic Monitoring
por: Becker, Lucas, et al.
Publicado: (2021)

Applying phasor approach analysis of multiphoton FLIM measurements to probe the metabolic activity of three-dimensional in vitro cell culture models
por: Lakner, Pirmin H., et al.
Publicado: (2017)

Elastogenesis at the onset of human cardiac valve development
por: Votteler, Miriam, et al.
Publicado: (2013)

Imaging of α-Synuclein Aggregates in a Rat Model of Parkinson’s Disease Using Raman Microspectroscopy
por: Sevgi, Fide, et al.
Publicado: (2021)

Raman microspectroscopy and Raman imaging reveal biomarkers specific for thoracic aortic aneurysms
por: Sugiyama, Kaori, et al.
Publicado: (2021)

Monitoring the macrophage response towards biomaterial implants using label-free imaging
por: Lu, Chuan-en, et al.
Publicado: (2023)

Lipidome profiling with Raman microspectroscopy identifies macrophage response to surface topographies of implant materials
por: Feuerer, Nora, et al.
Publicado: (2021)

Non-contact, Label-free Monitoring of Cells and Extracellular Matrix using Raman Spectroscopy
por: Votteler, Miriam, et al.
Publicado: (2012)

Visualizing tropoelastin in a long-term human elastic fibre cell culture model
por: Halm, M., et al.
Publicado: (2016)

Epigenetic Regulation of Myogenic Gene Expression by Heterochromatin Protein 1 Alpha
por: Sdek, Patima, et al.
Publicado: (2013)

WAT-on-a-chip integrating human mature white adipocytes for mechanistic research and pharmaceutical applications
por: Rogal, Julia, et al.
Publicado: (2020)

Green Chemistry for Biomimetic Materials: Synthesis and Electrospinning of High-Molecular-Weight Polycarbonate-Based Nonisocyanate Polyurethanes
por: Visser, Dmitri, et al.
Publicado: (2022)

Three Water Restriction Schedules Used in Rodent Behavioral Tasks Transiently Impair Growth and Differentially Evoke a Stress Hormone Response without Causing Dehydration
por: Vasilev, Dmitrii, et al.
Publicado: (2021)

Raman Microspectroscopy Identifies Biochemical Activation Fingerprints in THP-1- and PBMC-Derived Macrophages
por: Feuerer, Nora, et al.
Publicado: (2022)

Autologous Human Immunocompetent White Adipose Tissue‐on‐Chip
por: Rogal, Julia, et al.
Publicado: (2022)

Interactions between Nitric Oxide and Hyaluronan Implicate the Migration of Breast Cancer Cells
por: Alsharabasy, Amir M., et al.
Publicado: (2022)

Marker-Independent Monitoring of in vitro and in vivo Degradation of Supramolecular Polymers Applied in Cardiovascular in situ Tissue Engineering
por: Marzi, Julia, et al.
Publicado: (2022)

Electrospun poly(d/l-lactide-co-l-lactide) hybrid matrix: a novel scaffold material for soft tissue engineering
por: Kluger, Petra J., et al.
Publicado: (2010)

The Role of Macrophages in the Infarcted Myocardium: Orchestrators of ECM Remodeling
por: O'Rourke, Sinead A., et al.
Publicado: (2019)

Data-Driven Identification of Biomarkers for In Situ Monitoring of Drug Treatment in Bladder Cancer Organoids
por: Becker, Lucas, et al.
Publicado: (2022)

The Use of Collagen-Based Materials in Bone Tissue Engineering
por: Fan, Lu, et al.
Publicado: (2023)

An Orally Administrated Hyaluronan Functionalized Polymeric Hybrid Nanoparticle System for Colon-Specific Drug Delivery
por: Kotla, Niranjan G., et al.
Publicado: (2019)

Controlled and tuneable drug release from electrospun fibers and a non-invasive approach for cytotoxicity testing
por: Piccirillo, G., et al.
Publicado: (2019)

A Platform of Patient-Derived Microtumors Identifies Individual Treatment Responses and Therapeutic Vulnerabilities in Ovarian Cancer
por: Anderle, Nicole, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_mcigc9vls5itockd3a65l02pn4