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Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity

Wiskott-Aldrich syndrome (WAS) is an immune pathology associated with mutations in WAS protein (WASp) or in WASp interacting protein (WIP). Together with the small GTPase Cdc42 and other effectors, these proteins participate in the remodelling of the actin network downstream of BCR engagement. Here...

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Detalles Bibliográficos
Autores principales: Burbage, Marianne, Gasparrini, Francesca, Aggarwal, Shweta, Gaya, Mauro, Arnold, Johan, Nair, Usha, Way, Michael, Bruckbauer, Andreas, Batista, Facundo D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770159/
https://www.ncbi.nlm.nih.gov/pubmed/29337666
http://dx.doi.org/10.7554/eLife.26556