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Optic Nerve Regeneration After Crush Remodels the Injury Site: Molecular Insights From Imaging Mass Spectrometry

PURPOSE: Mammalian central nervous system axons fail to regenerate after injury. Contributing factors include limited intrinsic growth capacity and an inhibitory glial environment. Inflammation-induced optic nerve regeneration (IIR) is thought to boost retinal ganglion cell (RGC) intrinsic growth ca...

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Detalles Bibliográficos
Autores principales: Stark, David T., Anderson, David M. G., Kwong, Jacky M. K., Patterson, Nathan Heath, Schey, Kevin L., Caprioli, Richard M., Caprioli, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770179/
https://www.ncbi.nlm.nih.gov/pubmed/29340649
http://dx.doi.org/10.1167/iovs.17-22509