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Identifying Corneal Infections in Formalin-Fixed Specimens Using Next Generation Sequencing

PURPOSE: We test the ability of next-generation sequencing, combined with computational analysis, to identify a range of organisms causing infectious keratitis. METHODS: This retrospective study evaluated 16 cases of infectious keratitis and four control corneas in formalin-fixed tissues from the pa...

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Detalles Bibliográficos
Autores principales: Li, Zhigang, Breitwieser, Florian P., Lu, Jennifer, Jun, Albert S., Asnaghi, Laura, Salzberg, Steven L., Eberhart, Charles G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770184/
https://www.ncbi.nlm.nih.gov/pubmed/29340642
http://dx.doi.org/10.1167/iovs.17-21617