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Endothelial Nitric Oxide Synthase-Independent Pleiotropic Effects of Pitavastatin Against Atherogenesis and Limb Ischemia in Mice

Aim: Statins have a protective impact against cardiovascular diseases through not only lipid-lowering effects but also pleiotropic effects, including activation of the endothelial nitric oxide synthase (eNOS) system. We aimed to clarify the protective effects of a statin against atherogenesis and is...

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Detalles Bibliográficos
Autores principales: Mitsuhashi, Takeshi, Uemoto, Ryoko, Ishikawa, Kazue, Yoshida, Sumiko, Ikeda, Yasumasa, Yagi, Shusuke, Matsumoto, Toshio, Akaike, Masashi, Aihara, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770225/
https://www.ncbi.nlm.nih.gov/pubmed/28592707
http://dx.doi.org/10.5551/jat.37747