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Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions

Nuclear RNA metabolism is influenced by protein complexes connecting to both RNA-productive and -destructive pathways. The ZC3H18 protein binds the cap-binding complex (CBC), universally present on capped RNAs, while also associating with the nuclear exosome targeting (NEXT) complex, linking to RNA...

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Detalles Bibliográficos
Autores principales: Winczura, Kinga, Schmid, Manfred, Iasillo, Claudia, Molloy, Kelly R., Harder, Lea Mørch, Andersen, Jens S., LaCava, John, Jensen, Torben Heick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770337/
https://www.ncbi.nlm.nih.gov/pubmed/29298432
http://dx.doi.org/10.1016/j.celrep.2017.12.037