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Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions
Nuclear RNA metabolism is influenced by protein complexes connecting to both RNA-productive and -destructive pathways. The ZC3H18 protein binds the cap-binding complex (CBC), universally present on capped RNAs, while also associating with the nuclear exosome targeting (NEXT) complex, linking to RNA...
Autores principales: | Winczura, Kinga, Schmid, Manfred, Iasillo, Claudia, Molloy, Kelly R., Harder, Lea Mørch, Andersen, Jens S., LaCava, John, Jensen, Torben Heick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770337/ https://www.ncbi.nlm.nih.gov/pubmed/29298432 http://dx.doi.org/10.1016/j.celrep.2017.12.037 |
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