Fragile X Mental Retardation Protein Regulates Activity-Dependent Membrane Trafficking and Trans-Synaptic Signaling Mediating Synaptic Remodeling

Fragile X syndrome (FXS) is the leading monogenic cause of autism and intellectual disability. The disease arises through loss of fragile X mental retardation protein (FMRP), which normally exhibits peak expression levels in early-use critical periods, and is required for activity-dependent synaptic...

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Detalles Bibliográficos
Autores principales: Sears, James C., Broadie, Kendal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770364/
https://www.ncbi.nlm.nih.gov/pubmed/29375303
http://dx.doi.org/10.3389/fnmol.2017.00440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770364/
https://www.ncbi.nlm.nih.gov/pubmed/29375303
http://dx.doi.org/10.3389/fnmol.2017.00440

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