Negative Effects of Chronic Rapamycin Treatment on Behavior in a Mouse Model of Fragile X Syndrome

Fragile X syndrome (FXS), the most common form of inherited intellectual disability, is also highly associated with autism spectrum disorders (ASD). It is caused by expansion of a CGG repeat sequence on the X chromosome resulting in silencing of the FMR1 gene. This is modeled in the mouse by deletio...

Descripción completa

Detalles Bibliográficos
Autores principales: Saré, Rachel M., Song, Alex, Loutaev, Inna, Cook, Anna, Maita, Isabella, Lemons, Abigail, Sheeler, Carrie, Smith, Carolyn B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770365/
https://www.ncbi.nlm.nih.gov/pubmed/29375310
http://dx.doi.org/10.3389/fnmol.2017.00452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770365/
https://www.ncbi.nlm.nih.gov/pubmed/29375310
http://dx.doi.org/10.3389/fnmol.2017.00452

Ejemplares similares