Cargando…

Negative Effects of Chronic Rapamycin Treatment on Behavior in a Mouse Model of Fragile X Syndrome

Fragile X syndrome (FXS), the most common form of inherited intellectual disability, is also highly associated with autism spectrum disorders (ASD). It is caused by expansion of a CGG repeat sequence on the X chromosome resulting in silencing of the FMR1 gene. This is modeled in the mouse by deletio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Saré, Rachel M., Song, Alex, Loutaev, Inna, Cook, Anna, Maita, Isabella, Lemons, Abigail, Sheeler, Carrie, Smith, Carolyn B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770365/ https://www.ncbi.nlm.nih.gov/pubmed/29375310 http://dx.doi.org/10.3389/fnmol.2017.00452

Ejemplares similares

Behavioral and Molecular Consequences of Chronic Sleep Restriction During Development in Fragile X Mice
por: Saré, R. Michelle, et al.
Publicado: (2022)

Chronic Sleep Restriction in Developing Male Mice Results in Long Lasting Behavior Impairments
por: Saré, Rachel Michelle, et al.
Publicado: (2019)

Effects of Treatment With Hypnotics on Reduced Sleep Duration and Behavior Abnormalities in a Mouse Model of Fragile X Syndrome
por: Saré, Rachel Michelle, et al.
Publicado: (2022)

Comparative Behavioral Phenotypes of Fmr1 KO, Fxr2 Het, and Fmr1 KO/Fxr2 Het Mice
por: Saré, Rachel Michelle, et al.
Publicado: (2019)

Regional rates of brain protein synthesis are unaltered in dexmedetomidine sedated young men with fragile X syndrome: A L-[1-(11)C]leucine PET study
por: Schmidt, Kathleen C., et al.
Publicado: (2020)

Deficient Sleep in Mouse Models of Fragile X Syndrome
por: Saré, R. Michelle, et al.
Publicado: (2017)

Confirmation of Decreased Rates of Cerebral Protein Synthesis In Vivo in a Mouse Model of Tuberous Sclerosis Complex
por: Saré, Rachel Michelle, et al.
Publicado: (2022)

Sleep Duration in Mouse Models of Neurodevelopmental Disorders
por: Saré, Rachel Michelle, et al.
Publicado: (2020)

Sex-Selective Effects on Behavior in a Mouse Model of Tuberous Sclerosis Complex
por: Saré, Rachel Michelle, et al.
Publicado: (2020)

Behavior Testing in Rodents: Highlighting Potential Confounds Affecting Variability and Reproducibility
por: Saré, Rachel Michelle, et al.
Publicado: (2021)

Implications of maraviroc and/or rapamycin in a mouse model of fragility
por: Pérez-Martínez, Laura, et al.
Publicado: (2020)

Mouse models of the fragile X premutation and fragile X-associated tremor/ataxia syndrome
por: Berman, Robert F, et al.
Publicado: (2014)

Distinctive behavioral and cellular responses to fluoxetine in the mouse model for Fragile X syndrome
por: Uutela, Marko, et al.
Publicado: (2014)

Paradoxical effect of baclofen on social behavior in the fragile X syndrome mouse model
por: Zeidler, Shimriet, et al.
Publicado: (2018)

The mouse model of fragile X syndrome exhibits deficits in contagious itch behavior
por: Gonzales-Rojas, Rodrigo, et al.
Publicado: (2020)

Gaboxadol Normalizes Behavioral Abnormalities in a Mouse Model of Fragile X Syndrome
por: Cogram, Patricia, et al.
Publicado: (2019)

Mouse models of fragile X-related disorders
por: Willemsen, Rob, et al.
Publicado: (2023)

Early behavioral and physiological markers of social anxiety in infants with fragile X syndrome
por: Black, Conner J., et al.
Publicado: (2021)

Early negative affect in males and females with fragile X syndrome: implications for anxiety and autism
por: Wall, Carla A., et al.
Publicado: (2019)

Visual Behavior Impairments as an Aberrant Sensory Processing in the Mouse Model of Fragile X Syndrome
por: Felgerolle, Chloé, et al.
Publicado: (2019)

Cerebral Protein Synthesis in a Knockin Mouse Model of the Fragile X Premutation
por: Qin, Mei, et al.
Publicado: (2014)

Fragile X syndrome and fragile X-associated disorders
por: Rajaratnam, Akash, et al.
Publicado: (2017)

Persistent astrocyte activation in the fragile X mouse cerebellum
por: Pacey, Laura K. K., et al.
Publicado: (2015)

Hyperexcitability of Sensory Neurons in Fragile X Mouse Model
por: Deng, Pan-Yue, et al.
Publicado: (2021)

R-Baclofen Reverses a Social Behavior Deficit and Elevated Protein Synthesis in a Mouse Model of Fragile X Syndrome
por: Qin, Mei, et al.
Publicado: (2015)

FRAGILE X MENTAL RETARDATION PROTEIN REPLACEMENT RESTORES HIPPOCAMPAL SYNAPTIC FUNCTION IN A MOUSE MODEL OF FRAGILE X SYNDROME
por: Zeier, Zane, et al.
Publicado: (2009)

Timing of Expansion of Fragile X Premutation Alleles During Intergenerational Transmission in a Mouse Model of the Fragile X-Related Disorders
por: Zhao, Xiao-Nan, et al.
Publicado: (2018)

Dysregulated Prefrontal Cortex Inhibition in Prepubescent and Adolescent Fragile X Mouse Model
por: Kramvis, Ioannis, et al.
Publicado: (2020)

Limbic Epileptogenesis in a Mouse Model of Fragile X Syndrome
por: Qiu, Li-Feng, et al.
Publicado: (2009)

Fragile X Syndrome
por: McLennan, Yingratana, et al.
Publicado: (2011)

Targeting fragile X
por: Gantois, Ilse, et al.
Publicado: (2002)

Fragile X Premutation
por: Tassone, Flora, et al.
Publicado: (2014)

Fragile X Syndrome
por: Saldarriaga, Wilmar, et al.
Publicado: (2014)

From circuits to behavior: Amygdala dysfunction in fragile X syndrome
por: Svalina, Matthew N., et al.
Publicado: (2023)

Deficits in Tactile Learning in a Mouse Model of Fragile X Syndrome
por: Arnett, Megan T., et al.
Publicado: (2014)

Lovastatin, not Simvastatin, Corrects Core Phenotypes in the Fragile X Mouse Model
por: Muscas, Melania, et al.
Publicado: (2019)

Altered Gut Microbiota in a Fragile X Syndrome Mouse Model
por: Altimiras, Francisco, et al.
Publicado: (2021)

Fragile X mental retardation protein expression in Alzheimer’s disease
por: Renoux, Abigail J., et al.
Publicado: (2014)

Fragile X-Associated Neuropsychiatric Disorders (FXAND) in Young Fragile X Premutation Carriers
por: Aishworiya, Ramkumar, et al.
Publicado: (2022)

Clinic-Based Retrospective Analysis of Psychopharmacology for Behavior in Fragile X Syndrome
por: Berry-Kravis, Elizabeth, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_jisjmi97ru00dvrl4ii0cg0aqr