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Negative Effects of Chronic Rapamycin Treatment on Behavior in a Mouse Model of Fragile X Syndrome

Fragile X syndrome (FXS), the most common form of inherited intellectual disability, is also highly associated with autism spectrum disorders (ASD). It is caused by expansion of a CGG repeat sequence on the X chromosome resulting in silencing of the FMR1 gene. This is modeled in the mouse by deletio...

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Detalles Bibliográficos
Autores principales:	Saré, Rachel M., Song, Alex, Loutaev, Inna, Cook, Anna, Maita, Isabella, Lemons, Abigail, Sheeler, Carrie, Smith, Carolyn B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770365/ https://www.ncbi.nlm.nih.gov/pubmed/29375310 http://dx.doi.org/10.3389/fnmol.2017.00452

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