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Bergenin, Acting as an Agonist of PPARγ, Ameliorates Experimental Colitis in Mice through Improving Expression of SIRT1, and Therefore Inhibiting NF-κB-Mediated Macrophage Activation

Bergenin, isolated from the herb of Saxifraga stolonifera Curt. (Hu-Er-Cao), has anti-inflammatory, antitussive and wound healing activities. The aim of the present study was to identify the effect of bergenin on experimental colitis, and explored the related mechanisms. Our results showed that oral...

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Detalles Bibliográficos
Autores principales: Wang, Kai, Li, Yun-fan, Lv, Qi, Li, Xi-ming, Dai, Yue, Wei, Zhi-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770370/
https://www.ncbi.nlm.nih.gov/pubmed/29375382
http://dx.doi.org/10.3389/fphar.2017.00981