Cargando…
Bergenin, Acting as an Agonist of PPARγ, Ameliorates Experimental Colitis in Mice through Improving Expression of SIRT1, and Therefore Inhibiting NF-κB-Mediated Macrophage Activation
Bergenin, isolated from the herb of Saxifraga stolonifera Curt. (Hu-Er-Cao), has anti-inflammatory, antitussive and wound healing activities. The aim of the present study was to identify the effect of bergenin on experimental colitis, and explored the related mechanisms. Our results showed that oral...
Autores principales: | Wang, Kai, Li, Yun-fan, Lv, Qi, Li, Xi-ming, Dai, Yue, Wei, Zhi-feng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770370/ https://www.ncbi.nlm.nih.gov/pubmed/29375382 http://dx.doi.org/10.3389/fphar.2017.00981 |
Ejemplares similares
-
Bergenin ameliorates airway inflammation and remodeling in asthma by activating SIRT1 in macrophages to regulate the NF-κB pathway
por: Huang, Dan, et al.
Publicado: (2022) -
Chitosan Oligosaccharides Alleviate Colitis by Regulating Intestinal Microbiota and PPARγ/SIRT1-Mediated NF-κB Pathway
por: Guo, Congcong, et al.
Publicado: (2022) -
Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway
por: Xia, Yujing, et al.
Publicado: (2020) -
Yarrow oil ameliorates ulcerative colitis in mice model via regulating the NF‐κB and PPAR-γ pathways
por: Mohamed, Maged E., et al.
Publicado: (2021) -
Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway
por: Xiang, Shihao, et al.
Publicado: (2020)