Comparative Whole-Genomic Analysis of an Ancient L2 Lineage Mycobacterium tuberculosis Reveals a Novel Phylogenetic Clade and Common Genetic Determinants of Hypervirulent Strains

Background: Development of improved therapeutics against tuberculosis (TB) is hindered by an inadequate understanding of the relationship between disease severity and genetic diversity of its causative agent, Mycobacterium tuberculosis. We previously isolated a hypervirulent M. tuberculosis strain H...

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Detalles Bibliográficos
Autores principales: Rajwani, Rahim, Yam, Wing Cheong, Zhang, Ying, Kang, Yu, Wong, Barry Kin Chung, Leung, Kenneth Siu Sing, Tam, Kingsley King Gee, Tulu, Ketema Tafess, Zhu, Li, Siu, Gilman Kit Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770396/
https://www.ncbi.nlm.nih.gov/pubmed/29376038
http://dx.doi.org/10.3389/fcimb.2017.00539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770396/
https://www.ncbi.nlm.nih.gov/pubmed/29376038
http://dx.doi.org/10.3389/fcimb.2017.00539

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