DNA methyltransferase inhibition upregulates MHC-I to potentiate cytotoxic T lymphocyte responses in breast cancer

Potentiating anti-tumor immunity by inducing tumor inflammation and T cell-mediated responses are a promising area of cancer therapy. Immunomodulatory agents that promote these effects function via a wide variety of mechanisms, including upregulation of antigen presentation pathways. Here, we show t...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Na, Nixon, Mellissa J., Gonzalez-Ericsson, Paula I., Sanchez, Violeta, Opalenik, Susan R., Li, Huili, Zahnow, Cynthia A., Nickels, Michael L., Liu, Fei, Tantawy, Mohammed N., Sanders, Melinda E., Manning, H. Charles, Balko, Justin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770411/
https://www.ncbi.nlm.nih.gov/pubmed/29339738
http://dx.doi.org/10.1038/s41467-017-02630-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770411/
https://www.ncbi.nlm.nih.gov/pubmed/29339738
http://dx.doi.org/10.1038/s41467-017-02630-w

Ejemplares similares