Loss of disease tolerance during Citrobacter rodentium infection is associated with impaired epithelial differentiation and hyperactivation of T cell responses

Citrobacter rodentium is an intestinal mouse pathogen widely used as a model to study the mucosal response to infection. Inbred mouse strains suffer one of two fates following infection: self-limiting colitis or fatal diarrheal disease. We previously reported that Rspo2 is a major genetic determinan...

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Detalles Bibliográficos
Autores principales: Kang, Eugene, Zhou, Guangyan, Yousefi, Mitra, Cayrol, Romain, Xia, Jianguo, Gruenheid, Samantha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770458/
https://www.ncbi.nlm.nih.gov/pubmed/29339782
http://dx.doi.org/10.1038/s41598-017-17386-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770458/
https://www.ncbi.nlm.nih.gov/pubmed/29339782
http://dx.doi.org/10.1038/s41598-017-17386-y

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