An Intracellular Ammonium Transporter Is Necessary for Replication, Differentiation, and Resistance to Starvation and Osmotic Stress in Trypanosoma cruzi

Trypanosoma cruzi, the etiologic agent of Chagas disease, undergoes drastic metabolic changes when it transits between a vector and mammalian hosts. Amino acid catabolism leads to the production of ammonium (NH(4)(+)), which needs to be detoxified. However, T. cruzi does not possess a urea cycle, an...

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Detalles Bibliográficos
Autores principales: Cruz-Bustos, Teresa, Potapenko, Evgeniy, Storey, Melissa, Docampo, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770540/
https://www.ncbi.nlm.nih.gov/pubmed/29359189
http://dx.doi.org/10.1128/mSphere.00377-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770540/
https://www.ncbi.nlm.nih.gov/pubmed/29359189
http://dx.doi.org/10.1128/mSphere.00377-17

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