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Simultaneous Binding of Multiple EF-Tu Copies to Translating Ribosomes in Live Escherichia coli

In bacteria, elongation factor Tu is a translational cofactor that forms ternary complexes with aminoacyl-tRNA (aa-tRNA) and GTP. Binding of a ternary complex to one of four flexible L7/L12 units on the ribosome tethers a charged tRNA in close proximity to the ribosomal A site. Two sequential tests...

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Detalles Bibliográficos
Autores principales: Mustafi, Mainak, Weisshaar, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770553/
https://www.ncbi.nlm.nih.gov/pubmed/29339430
http://dx.doi.org/10.1128/mBio.02143-17