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Simultaneous Binding of Multiple EF-Tu Copies to Translating Ribosomes in Live Escherichia coli
In bacteria, elongation factor Tu is a translational cofactor that forms ternary complexes with aminoacyl-tRNA (aa-tRNA) and GTP. Binding of a ternary complex to one of four flexible L7/L12 units on the ribosome tethers a charged tRNA in close proximity to the ribosomal A site. Two sequential tests...
Autores principales: | Mustafi, Mainak, Weisshaar, James C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770553/ https://www.ncbi.nlm.nih.gov/pubmed/29339430 http://dx.doi.org/10.1128/mBio.02143-17 |
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