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The Role of Ferroptosis in Cancer Development and Treatment Response

Ferroptosis is a process driven by accumulated iron-dependent lipid ROS that leads to cell death, which is a distinct regulated cell death comparing to other cell death. The lethal metabolic imbalance resulted from GSH depletion or inactivation of glutathione peroxidase 4 is the executor of ferropto...

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Detalles Bibliográficos
Autores principales: Lu, Bin, Chen, Xiao Bing, Ying, Mei Dan, He, Qiao Jun, Cao, Ji, Yang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770584/
https://www.ncbi.nlm.nih.gov/pubmed/29375387
http://dx.doi.org/10.3389/fphar.2017.00992