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Atypical E2Fs inhibit tumor angiogenesis

Atypical E2F transcription factors (E2F7 and E2F8) function as key regulators of cell cycle progression and their inactivation leads to spontaneous cancer formation in mice. However, the mechanism of the tumor suppressor functions of E2F7/8 remain obscure. In this study we discovered that atypical E...

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Detalles Bibliográficos
Autores principales: Weijts, B G M W, Westendorp, B, Hien, B T, Martínez-López, L M, Zijp, M, Thurlings, I, Thomas, R E, Schulte-Merker, S, Bakker, W J, de Bruin, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770600/
https://www.ncbi.nlm.nih.gov/pubmed/28925392
http://dx.doi.org/10.1038/onc.2017.336