Ribosome biogenesis mediates antitumor activity of flavopiridol in CD44(+)/CD24(−) breast cancer stem cells

Flavopiridol is a synthetically produced flavonoid that potently inhibits the proliferation of human tumor cell lines. Flavopiridol exerts strong antitumor activity via several mechanisms, including the induction of cell cycle arrest and apoptosis, and the modulation of transcriptional regulation. T...

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Detalles Bibliográficos
Autores principales: Erol, Ayse, Acikgoz, Eda, Guven, Ummu, Duzagac, Fahriye, Turkkani, Ayten, Colcimen, Nese, Oktem, Gulperi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770605/
https://www.ncbi.nlm.nih.gov/pubmed/29422957
http://dx.doi.org/10.3892/ol.2017.7029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770605/
https://www.ncbi.nlm.nih.gov/pubmed/29422957
http://dx.doi.org/10.3892/ol.2017.7029

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