Turning the Old Adjuvant from Gel to Nanoparticles to Amplify CD8(+) T Cell Responses

Due to its safety and efficacy, aluminum hydroxide is used as an immune adjuvant in human vaccines for over 80 years. Being a Th2 stimulator, the classical gel‐like adjuvant, however, fails to generate CD8(+) T cell responses, which are important for cancer vaccines. Here, aluminum hydroxide is turn...

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Detalles Bibliográficos
Autores principales: Jiang, Hao, Wang, Qin, Li, Lin, Zeng, Qin, Li, Hanmei, Gong, Tao, Zhang, Zhirong, Sun, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770685/
https://www.ncbi.nlm.nih.gov/pubmed/29375970
http://dx.doi.org/10.1002/advs.201700426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770685/
https://www.ncbi.nlm.nih.gov/pubmed/29375970
http://dx.doi.org/10.1002/advs.201700426

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