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Turning the Old Adjuvant from Gel to Nanoparticles to Amplify CD8(+) T Cell Responses
Due to its safety and efficacy, aluminum hydroxide is used as an immune adjuvant in human vaccines for over 80 years. Being a Th2 stimulator, the classical gel‐like adjuvant, however, fails to generate CD8(+) T cell responses, which are important for cancer vaccines. Here, aluminum hydroxide is turn...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770685/ https://www.ncbi.nlm.nih.gov/pubmed/29375970 http://dx.doi.org/10.1002/advs.201700426 |