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GATA2 Deficiency and Epstein–Barr Virus Disease
GATA2 is a transcription factor that binds to the promoter of hematopoietic genes. Mutations in one copy of the gene are associated with haploinsufficiency and reduced levels of protein. This results in reduced numbers of several cell types important for immune surveillance including dendritic cells...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770745/ https://www.ncbi.nlm.nih.gov/pubmed/29375553 http://dx.doi.org/10.3389/fimmu.2017.01869 |