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Pathophysiological Role of Purines and Pyrimidines in Neurodevelopment: Unveiling New Pharmacological Approaches to Congenital Brain Diseases

In recent years, a substantial body of evidence has emerged demonstrating that purine and pyrimidine synthesis and metabolism play major roles in controlling embryonic and fetal development and organogenesis. Dynamic and time-dependent changes in the expression of purine metabolizing enzymes (such a...

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Detalles Bibliográficos
Autores principales: Fumagalli, Marta, Lecca, Davide, Abbracchio, Maria P., Ceruti, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770749/
https://www.ncbi.nlm.nih.gov/pubmed/29375373
http://dx.doi.org/10.3389/fphar.2017.00941