R-Baclofen Reverses Cognitive Deficits and Improves Social Interactions in Two Lines of 16p11.2 Deletion Mice

Human chromosome 16p11.2 microdeletion is among the most common gene copy number variations (CNVs) known to confer risk for intellectual disability (ID) and autism spectrum disorder (ASD) and affects an estimated 3 in 10 000 people. Caused by a single copy deletion of ~27 genes, 16p11.2 microdeletio...

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Detalles Bibliográficos
Autores principales: Stoppel, Laura J, Kazdoba, Tatiana M, Schaffler, Melanie D, Preza, Anthony R, Heynen, Arnold, Crawley, Jacqueline N, Bear, Mark F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770771/
https://www.ncbi.nlm.nih.gov/pubmed/28984295
http://dx.doi.org/10.1038/npp.2017.236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770771/
https://www.ncbi.nlm.nih.gov/pubmed/28984295
http://dx.doi.org/10.1038/npp.2017.236

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