Autophagy controls mesenchymal stem cell properties and senescence during bone aging

Bone marrow‐derived mesenchymal stem cells (BMMSCs) exhibit degenerative changes, including imbalanced differentiation and reduced proliferation during aging, that contribute to age‐related bone loss. We demonstrate here that autophagy is significantly reduced in aged BMMSCs compared with young BMMS...

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Detalles Bibliográficos
Autores principales: Ma, Yang, Qi, Meng, An, Ying, Zhang, Liqiang, Yang, Rui, Doro, Daniel H, Liu, Wenjia, Jin, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770781/
https://www.ncbi.nlm.nih.gov/pubmed/29210174
http://dx.doi.org/10.1111/acel.12709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770781/
https://www.ncbi.nlm.nih.gov/pubmed/29210174
http://dx.doi.org/10.1111/acel.12709

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