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Autophagy controls mesenchymal stem cell properties and senescence during bone aging
Bone marrow‐derived mesenchymal stem cells (BMMSCs) exhibit degenerative changes, including imbalanced differentiation and reduced proliferation during aging, that contribute to age‐related bone loss. We demonstrate here that autophagy is significantly reduced in aged BMMSCs compared with young BMMS...
Autores principales: | Ma, Yang, Qi, Meng, An, Ying, Zhang, Liqiang, Yang, Rui, Doro, Daniel H, Liu, Wenjia, Jin, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770781/ https://www.ncbi.nlm.nih.gov/pubmed/29210174 http://dx.doi.org/10.1111/acel.12709 |
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